Desmopressin (DDAVP) and factor VIII

Use of desmopressin (DDAVP) during early pregnancy in factor VIII-deficient women.

3. Wen FQ, Jabbar AA, Chen YX, Kazarian T, Patel DA, Valentino LA. C-myc proto-oncogene expression in hemophilic synovitis: in vitro studies of the effects of iron and ceramide. Blood. 2002;100:912-916. 4. Nishiya K. Stimulation of human synovial cell DNA synthesis by iron. J Rheumatol. 1994;21:1802-1807. 5. Cruz E, Vieira J, Gonçalves R, et al. Involvement of the MHC region in the genetic regu...

Low-dose intranasal desmopressin (DDAVP) for uremic bleeding.

FACTOR V AND VIII INHIBITOR IN PATIENTS WITH COMBINED FACTOR V AND VIII DEFICIENCY

Patients with coagulation factor(s) deficiency who use coagulation therapy are susceptible to forming inhibitors against coagulation factor(s). In this survey we detected factor V and VIII inhibitor in ten patients with combined deficiency of factors V and VIII from north east of Iran (Khorassan province). It was revealed in our survey that eight patients had both factor V and factor VIII i...

Coronary Spastic Angina Induced after Oral Desmopressin (DDAVP) Administration

A 60-year-old man was prescribed oral desmopressin (1-deamino-8-D-arginine vasopressin acetate trihydrate; DDAVP) for nocturnal polyuria. One week after starting to take desmopressin, he frequently felt chest pain while resting. Coronary angiography revealed no organic stenosis; however, an acetylcholine provocation test showed severe coronary spasm with ST elevation. He was diagnosed with coro...

Combined Factor V and VIII Deficiency

This review summarizes current data on the pathomechanisms and new genetic findings of combined factor V and VIII deficiency (CF5F8D). Congenital haemorrhagic disorders characterized by deficiency of two clotting factors comprise an interesting group. Among dual coagulation disorders, CF5F8D is the most common type. For the first time combined factor V and VIII deficiency (F5F8D) was reported b...